Search results for "Sensitivity analyses"

showing 5 items of 5 documents

Cost-Effectiveness Analysis of Different Testing Strategies that Use Antibody Levels to Detect Chronic Hepatitis C in Blood Donors.

2016

Aim. We conducted a cost-effectiveness analysis of seven hepatitis C virus (HCV) testing strategies in blood donors. Methods. Three of the seven strategies were based on HCV diagnosis and reporting guidelines in Mexico and four were from previous and current recommendations outlined by the CDC. The strategies that were evaluated determine antibody levels according to the signal-to-cut-off (S/CO) ratio and use reflex Immunoblot (IMB) or HCV RNA tests to confirm true positive (TP) cases of chronic HCV infection. Costs were calculated from the perspective of the Mexican Institute of Social Security (IMSS). A decision tree model was developed to estimate the expected number of true positive cas…

RNA virusesDecision AnalysisPhysiologyEconomicsCost-Benefit AnalysisSocial Scienceslcsh:MedicineBlood DonorsHepacivirusmedicine.disease_causeBiochemistryHepatitis0302 clinical medicineImmune Physiology030212 general & internal medicineChroniclcsh:SciencePathology and laboratory medicinehealth care economics and organizationsMultidisciplinaryImmune System ProteinsCost–benefit analysisHepatitis C virusLiver DiseaseCost-effectiveness analysisMedical microbiologyHepatitis CHCV AntibodyInfectious DiseasesVirusesEngineering and TechnologyBlood Banks030211 gastroenterology & hepatologyPathogensInfectionManagement EngineeringResearch Articlemedicine.medical_specialtyGeneral Science & TechnologyHepatitis C virusImmunologyCost-Effectiveness AnalysisImmunoblottingChronic Liver Disease and CirrhosisMolecular Probe TechniquesAntibody levelResearch and Analysis MethodsMicrobiologyAntibodies03 medical and health sciencesChronic hepatitisHepatitis - CClinical ResearchInternal medicineparasitic diseasesmedicineHumansImmunoassaysMolecular Biology TechniquesSensitivity analysesMolecular BiologyMedicine and health sciencesBiology and life sciencesFlavivirusesbusiness.industryDecision Treeslcsh:RHepatitis C antibodyOrganismsViral pathogensProteinsHepatitis C ChronicHepatitis C AntibodiesHepatitis virusesEconomic AnalysisMicrobial pathogensHealth CareEmerging Infectious DiseasesCost Effectiveness ResearchHealth Care FacilitiesImmunologyImmunologic Techniqueslcsh:QbusinessDigestive Diseases
researchProduct

Cost-effectiveness of screening for colorectal cancer in France using a guaiac test versus an immunochemical test

2010

Objectives: The aim of this study was to compare the cost and the effectiveness of two biennial fecal occult blood screening tests for colorectal cancer: a guaiac nonrehydrated test (G-FOBT) and an immunochemical test (I-FOBT) with the absence of screening.Methods: A Markov model was developed to compare these strategies in a general population of subjects aged 50 to 74 over a 20-year period.Results: Compared with the absence of screening, G-FOBT and I-FOBT were associated with a decrease in colorectal cancer mortality of 17.4 percent and 25.2 percent, respectively. With regard to cost-effectiveness, expressed as cost per life-year gained, I-FOBT was the most effective and most costly alter…

medicine.medical_specialtyColorectal cancerCost effectivenessCost-Benefit Analysishealth care facilities manpower and serviceseducationPopulationImmunologic TestsSensitivity and SpecificityInternal medicinemedicineHumansMass ScreeningeducationSensitivity analyseshealth care economics and organizationsMass screeningAgedGynecologyeducation.field_of_studybiologybusiness.industryHealth PolicyEurosMiddle Agedmedicine.diseasebiology.organism_classificationMarkov Chainsdigestive system diseasesTest (assessment)surgical procedures operativeFecal occult blood screeningOccult BloodIndicators and ReagentsFranceColorectal NeoplasmsGuaiacbusinessInternational Journal of Technology Assessment in Health Care
researchProduct

Competition and cooperation for intermodal container transhipment: A network optimization approach

2018

Abstract This study presents an analysis of cross-border competition and cooperation between ports in Bangladesh and India. Nepal and Bhutan are countries without access to seaports — two landlocked countries in South Asia, depending solely on the Indian port of Kolkata for their international seaborne trade. Alternatives do exist in the Bangladeshi ports of Chittagong and Mongla but these are not exploited, in spite of trade agreements that allow access to a third country's port, and/or crossing the land of a third, intermediate, country. We formulate a mixed integer linear programming optimization model to find the optimum economic benefit of port users (serving Bhutan, Nepal and Northeas…

050210 logistics & transportationSouth asiaStrategy and Management05 social sciencesEconomics Econometrics and Finance (miscellaneous)General Decision SciencesTransportation010501 environmental sciencesManagement Science and Operations Research01 natural sciencesPort (computer networking)Competition (economics)Tourism Leisure and Hospitality Management0502 economics and businessContainer (abstract data type)BusinessBusiness and International ManagementLandlocked countryRobustness (economics)Integer programmingSensitivity analysesIndustrial organization0105 earth and related environmental sciencesResearch in Transportation Business & Management
researchProduct

Exploration of future changes of residential locations in an urban agglomeration using an individual-based simulation model (Mobisim)

2015

To ensure that housing supply is suitable to households’ needs and preferences represents a major planning concern. These needs and preferences depend on the households’ characteristics and on their lifecycle changes (union, birth, divorce…). Residential choice factors are numerous (housing and residential environment characteristics) and their role is often different according to the types of households. Residential dynamics involve a great variety of elements, in interaction with each other, and the causal relationships are difficult to identify. Thus, it is not possible to predict the households’ residential behaviour, nor their possible evolutions, without a suitable tool. To study intr…

Sensitivity analysesSimualtionChoix résidentielsModélisation[SHS.GEO] Humanities and Social Sciences/GeographyCalibrationAnalyse de sensibilitéMobisimParamétrageSatisfaction résidentielleModellingResidential mobilityMobilités résidentielles
researchProduct

Cost-effectiveness of bedaquiline in MDR and XDR tuberculosis in Italy

2016

ABSTRACT Objective: To evaluate the cost-effectiveness of bedaquiline plus background drug regimens (BR) for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) in Italy. Methods: A Markov model was adapted to the Italian setting to estimate the incremental cost-effectiveness ratio (ICER) of bedaquiline plus BR (BBR) versus BR in the treatment of MDR-TB and XDR-TB over 10 years, from both the National Health Service (NHS) and societal perspective. Cost-effectiveness was evaluated in terms of life-years gained (LYG). Clinical data were sourced from trials; resource consumption for compared treatments was modelled according to advice from an expert c…

medicine.medical_specialtyPediatricsTuberculosisCost effectivenessBedaquilinelcsh:Business03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSocietal perspectivemedicineOriginal Research Article030212 general & internal medicineResource consumptionSensitivity analysescost-effectivenessDisease treatmenthealth care economics and organizationsbusiness.industrylcsh:Public aspects of medicinelcsh:RA1-1270medicine.diseaseNational health serviceMDR tuberculosis030228 respiratory systemchemistryItalyEmergency medicineXDR tuberculosisOriginal ArticleBedaquilinebusinesslcsh:HF5001-6182Journal of Market Access & Health Policy
researchProduct